Abstract: As the wide band signal application popularizing, traditional ADC based on Nyquist sampling theory is limited, which can be conquered by compressed sensing theory. This paper presents an ADC based on compressed sensing theory, and put forward a calibration method to estimate the mismatch of multipath when reconstructing the original signal from compressed sensing measurement. The whole system is implemented in UMC 180 nm fabrication. It consists multipath to measure the input signal but quantized by a single quantizer. The quantizer is a SAR ADC which can work individually. The object is to design an ADC achieving 160 MHz sampling frequency and 12 bit ENOB with a sub-Nyquist quantizer. The whole system achieves a post-layout 160 MHz 10.25 ENOB with a figure of merit of 110 fJ/conv-step, and occupies 2.08. The SAR ADC achieves a post-layout 40 MHz 10.08 bit with a FOM of 56 fJ/conv-step. The simulation shows the correctness and effectiveness of the system structure and calibration method.