Abstract: This paper researches a predictive modulation based on the output ripple voltage across of the ESR of the capacitor for the boost DC-DC converter. Firstly, this paper introduces the converter has two voltage feedback loops, which samples the ripple voltage across ESR of capacitor without sampling current. Secondly, in order to improve the digital control performance, the predictive technique is used. With that technique, the converter has faster transient response and perturbation is decreased. And at the same time, to avoid sub-harmonic oscillation, voltage valley trailing-edge modulation is adopted. Finally, boost DC-DC converter is controlled by above techniques and the simulation results made by Simulink show that it has good stability and transient response performance under perturbation. No current sensor or slope compensation needed in the implementation, and the cost of the converter is effectively reduced.