Abstract: This paper demonstrates a novel highly integrated transmitter front-end based on microwave board. By using the field-circuit co-simulation analysis, the local oscillator link is analyzed, which makes the local oscillator have enough output power and good harmonic suppression. Full wave simulation tool (HFSS) is used to study the loss of signal path, the coupling between electromagnetic radiation and device. The Simulation results show, the third substrate integrated waveguide (SIW) BPF insertion loss is less than 3 dB, return loss greater than 15 dB. In addition, The EM coupling between the voltage controlled oscillator (VCO) output and the mixer RF port of the highest coupling is -56 dB, indicating very good isolation. Finally, we study the EMC design RF circuit board.