Abstract: In order to accelerate the design of power amplifier, reduce the network business cost and improve the quality of network.This paper, based on analyzing the technical target of base station power amplifier, mainly discusses design parameters and simulation process of base station PA.Presents a kind of method of simulating and designing PA using ADS software.Using the method to simulate and design the power gain, power additional efficiency, and third-order intermodulation of base station PA with a center frequency of 1960MHz.Meanwhile, compares simulation results with testing results.Resultsof comparison demonstrate that the method is feasible to simulate and design base station PA.