Abstract: In recent years,with the rapid development of online social network,it seems more and more popular that we use mobile devices to connect with other people.However,with the increased openness of operating systems,it makes realistic for worms and malicious software to propagate from one phone to another in mobile networks.So we need to find a strategy to efficiently contain the propagation of worms on the network.Existing strategies used for online social network cannot adapt to the structure of the real network.So we proposed a model based on target immunization,which can be used to design a more efficient counter-mechanism.Through analysis and comparing the infection situations under these two different strategies,we find that our model is faster and more efficient.