Abstract: In view of the limited effect of current methods to reduce the crosstalk of microstrip lines on PCB board, a method to reduce the crosstalk of microstrip lines using interdigital capacitance is proposed. In this method, an interdigital capacitor is added symmetrically to the two ends of the microstrip line to compensate the capacitance to balance the unequal coupling capacitance and inductance, thereby reducing the crosstalk. The simulation and actual measurement of remote crosstalk and insertion loss are carried out by using electromagnetic simulation software (HFSS) and vector network analyzer. The results show that the simulation and measurement are in good agreement. The addition of interdigital capacitor can reduce the remote crosstalk by more than 9 dB, and the production cost is low and easy to realize.