Abstract: According to the application characteristics of the wireless sensor network, the encoder and decoder algorithms of LDPC code are analyzed, the design methods of LDPC code used in wireless sensor network nodes are presented, in which (n, 3, 6) regular LDPC code, PEG-QC parity-check matrix, RU encoder algorithm, and Log-BP decoder algorithm are adopted.Finally, the methods are simulated on MATLAB, and the simulation results indicated that the methods are effective.