Abstract: Towards the deficiencies of collaborative functions in existing botnet detection architectures, a collaborative model based on multi-agent social was proposed. Three type roels (track Agent, detection Agent, counterattack Agent) were designed to simulate social roel of multi-agent social, and a botnet collaborative defence architecture on the basis of the proposed model was proposed. The analysis of a representative case indicates that the collaborative model given in this paper has the advantage of good extendibility, interaction, usability.